:: Volume 5, Issue 3 (9-2016) ::
Int J Med Invest 2016, 5(3): 121-125 Back to browse issues page
Improvement of sperm parameters after varicocelectomy: a single center study during six years
Ayoub Barzgarnezhad *, Bezad Feizzadeh kerigh, Mostafa Ahangaran
Department of Urology, Mazandaran University of Medical Sciences,Orthopedic Research center,Sari, Iran
Abstract:   (4137 Views)
Objective: One of the causes of male infertility is varicocele that has negative effects on sperm parameters.By doing varicocelectomy that it is an effective method for the treatment, there will be significant recovery in sperm parameters. The aim of this study is to evaluate sperm parameters before and after Varicocelectomy and a pregnancy rate in patients. Methods: This cross-sectional study has been performed on patients with primary and secondary infertility who underwent varicocelectomy during 2009-2014 in hospitals of Sari, north of Iran. Demographic data has been extracted from hospital records and necessary information about spermogram has been gathered according to a checklist designed for this purpose. We used a questionnaire that contained demographic characteristics of patients and values of variables before and after varicocelectomy. Finally all data have been analyzed statistically using SPSS ver.20.The significance level was set at 0.05. Results: of51 studied cases with the mean age of 37.3 years 50.98 percentswere above 40 years of old. 24 patients had varicocele grade II and 27 ones had grade three. Bilateral varicocelewas the dominant type in patients. The final finding represented that sperm indexes improved significantly after the varicocelectomy (p=0.001). Conclusion: Results of our study showed that varicocelectomy leads to significant differences in sperm parameters (count, motility and morphology), while the fertility rate also significantly increased.
Keywords: Infertility, Spermogram, Varicocele
Full-Text [PDF 242 kb]   (867 Downloads)    
Type of Study: Research | Subject: General
1. 1. Bach PV, Najari BB, Goldstein M. Varicocele - a case for early intervention.F1000Res. 2016 Jul 22;5. pii: F1000 Faculty Rev-1792. 2. Kucuk EV, Bindayi A, Boylu U, Onol FF, Gumus E. Randomised clinical trial of comparing effects of acupuncture and varicocelectomy on sperm parameters in infertile varicocele patients.Andrologia. 2016 Jan 21. 3. Hosseinifar H1, Sabbaghian M, Nasrabadi D, Modarresi T, Dizaj AV, Gourabi H. Study of the effect of varicocelectomy on spermproteinsexpression in patients with varicocele and poorspermquality by using two-dimensionalgelelectrophoresis. J Assist Reprod Genet. 2014 Jun;31(6):725-9. 4. Shabana W, Teleb M, Dawod T, Elsayed E, Desoky E, Shahin A, Eladl M, et al. Predictors of improvement in semen parameters after varicocelectomy for male subfertility: A prospective study.Can Urol Assoc J. 2015 Sep-Oct;9(9-10):E579-82. 5. Yazdani M, Hadi M, Abbasi H, Nourimahdavi K, Khalighinejad P, Mirsattari A, Efficacy of Varicocele Repair in Different Age Groups.Urology. 2015 Aug;86(2):273-5. 6. Fukuda T, Miyake H, Enatsu N, Matsushita K, Fujisawa M. Assessment of Time-dependent Changes in Semen Parameters in Infertile Men After Microsurgical Varicocelectomy.Urology. 2015 Jul;86(1):48-51. 7. Tavalaee M, Bahreinian M, Barekat F, Abbasi H, Nasr-Esfahani MH. Effect of varicocelectomy on sperm functional characteristics and DNA methylation.Andrologia. 2015 Oct;47(8):904-9. D 8. Esteves SC, Miyaoka R, Roque M, Agarwal A. Outcome of varicocele repair in men with nonobstructive azoospermia: systematic review and meta-analysis.Asian J Androl. 2016 Mar-Apr;18(2):246-53. 9. Pajovic B, Radojevic N. Prospective follow up of fertility after adolescent laparoscopic varicocelectomy.Eur Rev Med Pharmacol Sci. 2013 Apr;17(8):1060-3. 10. Schauer I, Madersbacher S, Jost R, Hübner WA, Imhof M. The impact of varicocelectomy on sperm parameters: a meta-analysis.J Urol. 2012 May;187(5):1540-7. 11. Jorsaraei G, Aghajani Mir M, Hajian K, Asghari Zadeh Ganji M. Effects of varicocelectomy on sperm parameters and fertility rate. JBUMS. 2006; 8 (1) :40-45 12. Sohrabi M.B, Amini A, Zolfaghari P, Yahyaei E. Effect of varicocelectomy on spermatogram index. Journal of Knowledge & Health 2014;9(2):47-51. 13. Daitch JA, Bedaiwy MA, Pasqualotto EB, Hendin BN, Hallak J, Falcone T, Thomas AJ, Nelson DR, Agarwal A: Varicocelectomy improves intra uterine insemination success rates in men with varicocele. J Urol 2001, 165(5):1510-1513. 14. Onozawa M, Endo F, Suetomi T, Takeshima H, Akaza H: Clinical study of varicocele: statistical analysis and the results of long-term follow-up. Int J Urol 2002, 9(8):455-461. 15. Kibar Y, Seckin B, Erduran D: The effects of subinguinal varicocelectomy on Kruger morphology and semen parameters. J Urol 2002, 168(3):1071-1074. O'Brien J, Bowles B, Kamal KM, Jarvi K, Zini A: Does the gonadotropin-releasing hormone stimulation test predict clinical outcomes after microsurgical varicocelectomy? Urology 2004, 63(6):1143-1147

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Volume 5, Issue 3 (9-2016) Back to browse issues page