[صفحه اصلی ]   [Archive]  
:: صفحه اصلي درباره نشريه آخرين شماره تمام شماره‌ها جستجو ثبت نام ارسال مقاله تماس با ما ::
:: دوره 6، شماره 4 - ( 9-1396 ) ::
جلد 6 شماره 4 صفحات 0-0 برگشت به فهرست نسخه ها
Hyper immunoglobulin-M Syndrome in children
چکیده:   (2742 مشاهده)
Introduction: Hyper immunoglobulin-M syndrome (HIGM) is a rare, x-linked recessive inherited disorder with Increased or normal serum IgM and decreased IgA, IgG and IgE and normal peripheral B cells. In this disease, we have defect in class switch recombination (CSR) and somatic hyper mutation that is caused by defects including the enzymes required for CSR and SHM. (SHM) Methods: To update about HIGM, PubMed and Google Scholar database were searched for term, X linked Hyper IgM syndrome and CD40 ligand. In our first search, we received about 90 updated articles, and then we distributed these articles among the authors. After reading the articles and sharing together, finally 33 articles were selected that fully related to the topic as references. Findings: In conclusion, HIGM is rare disease that starts early in life with lifelong recurrent attacks of various infections by a variety of symptoms, including lymph Adenopathy, vomiting, diarrhea, skin lesion and abdominal pain. Allogenic hematopoietic cell transplantation and BMT can be effective in these patients. Conclusion: In conclusion, HIGM is rare disease that starts early in life with lifelong recurrent attacks of various Infections by a variety of symptoms, including lymphadenopathy, vomiting, diarrhea, skin lesions and abdominal pain. Allogenic hematopoietic cell transplantation and BMT can be effective in these patients.
     
نوع مطالعه: مروری | موضوع مقاله: عمومى
ارسال نظر درباره این مقاله
نام کاربری یا پست الکترونیک شما:

CAPTCHA


XML     Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Sadeghnezhad R, Babaei hatkehlouei M, Golpour M, Jafarpour H. Hyper immunoglobulin-M Syndrome in children. Int J Med Invest. 2017; 6 (4)
URL: http://intjmi.com/article-1-289-fa.html

Hyper immunoglobulin-M Syndrome in children. . 1396; 6 (4)

URL: http://intjmi.com/article-1-289-fa.html



دوره 6، شماره 4 - ( 9-1396 ) برگشت به فهرست نسخه ها
International Journal of Medical Investigation
Persian site map - English site map - Created in 0.05 seconds with 32 queries by YEKTAWEB 3961