:: Volume 7, Issue 3 (9-2018) ::
Int J Med Invest 2018, 7(3): 32-42 Back to browse issues page
Evaluating The Relationship Between The Severity Of Psoriasis And The Prevalence Of Depression In Patients With Psoriasis Compared With Healthy Subjects Referred To Dermatology Clinics Of Gorgan In 2016-17
Peyman Rad * , Sadegh Ali Taziki
Resident of Psychiatry, Psychiatry and Behavioral Sciences Research Center, Faculty of Medicine ,Golestan University of Medical Sciences, Gorgan , Iran .
Abstract:   (6304 Views)
Introduction: Psoriasis is a systemic inflammatory disease and the most common recurrent chronic skin disease which affects almost 2% of the population and may occur at any age. This chronic disease causes changes in the appearance that impairs the patients’ mental image of themselves and causes rejection from society, isolation, personality disorders, depression, low self-esteem and weakened position of the person in the family. Due to the lack of permanent recovery of patients with medications, psychiatric interventions lead to improvements in the quality of life in these patients. An accurate assessment of the relationship between disease severity and psychopathology of it hasn’t been done in our society, so we decided to assess the relationship between disease severity and depression rate in patients with psoriasis referred to dermatology clinics is Gorgan in 2016-17 compared to healthy subjects. Method : In this case-control study, 68 patients with psoriasis referred to dermatology clinics in Gorgan in 1395 and 68 normal controls were examined for depression using standard Beck (Beck II ) test. Severity of the disease was calculated based on Psoriasis Area Severity Index Score (PASI Score). The data gathered was analyzed using statistical tests with confidence level of 0.95, and statistical power of 0.9 with SPSS software (version 18). Findings: This study evaluated 70 patients with psoriasis referred to dermatology clinics in Gorgan in 2016-17 and 70 healthy subjects as controls. In each group 22 subjects were male (31.4%) and 48 subjects were female (68.6%). Average disease severity was 35/17 ± 27 percent. With the increasing severity of psoriasis, the rate of depression is higher among patients. (P=0.0001) The rate of mild, moderate and severe depression in the case group was higher than the control group. This difference is statistically significant (p=0.0001) Conclusion: Depression symptoms are remarkably observed in psoriasis patients and the rate of these symptoms compared to healthy individuals is greater and these symptoms have a strong significant correlation with the severity of psoriasis.
Keywords: Depression, psoriasis, Beck II
Full-Text [PDF 544 kb]   (1717 Downloads)    
Type of Study: Research | Subject: General
References
1. 1- Zandi S, Shamsi Meymandi S, Sabouri Shahrebabak F.Evaluation of quality of life in patients with psoriasis. Dermatology and Cosmetic 2011; 2 (3): 166-173 2- Nasreen S , Ahmed I , Effendi S. Frequency and Magnitude of Anxiety and Depression in Patients with Psoriasis Vulgaris. Journal of the College of Physicians and Surgeons Pakistan 2008, Vol. 18 (7): 397-400. 3- Nabaei B, Safizadeh H, Hallaji Z. Evaluation of quality of life in psoriatic patients and comparison with healthy control. Iran J Dermatol 2002; 5: 15-21(Persian). 4- Sharma S , Bassi R , Singh A . A comparative study of depression and anxiety in psoriasis and other chronic skin diseases. Journal of Pakistan Association of Dermatologists 2011; 21 (4): 235-240. 5- F Chan , KM Ho , AHT Pang . Depression in Hong Kong Chinese patients with psoriasis . Hong Kong J. Dermatol. Venereol. (2009) 17, 69-77. 6- Tousi P, Ebrahimzadeh S, Zahyraldyn AR, Gachkar L. Study of Depression in patients with psoriasis admitted to Bu-Ali and Lukman hospitals in 1380-81. Pajoohandeh Journal. 2004; 8 (6): 9-15. 7- Anshayyh Sh, Kiani A,Yazdani A. Prevalence of depression and anxiety in patients with psoriasis. Skin Disease 2004; 6 (3): 23-1914. 8- Perrott SB, Murray AH, Lowe J, Mathieson CM. The psychosocial impact of psoriasis: physical severity, quality of life, and stigmatization. Physiol Behav. 2000 Sep 15;70(5):567-71 9- Kimball AB, Jacobson C, Weiss S, Vreeland MG, Wu Y. The psychosocial burden of psoriasis. Am J Clin Dermatol. 2005;6(6):383-92 10- Vardy D, Besser A, Amir M, Gesthalter B, Biton A, Buskila D. Experiences of stigmatization play a role in mediating the impact of disease severity on quality of life in psoriasis patients. Br J Dermatol. 2002 Oct;147(4):736-42. 11- Menter A. The effect of psoriasis on patients' quality of life and improvements associated with alefacept therapy. J Cutan Med Surg. 2004 Dec;8 Suppl 2:20-5. 12- Mazzotti E, Picardi A, Sampogna F, Sera F, Pasquini P, Abeni D; IDI Multipurpose Psoriasis Research on Vital Experiences study group. Sensitivity of the Dermatology Life Quality Index to clinical change in patients with psoriasis. Br J Dermatol. 2003 Aug;149(2):318-22. 13- Aqhakhani Nader, Baqhaee Rahim. Psychosocial Problems in Psoriasis Patients Admitted to Hospitals of Medical Sciences Universities of Tehran. Urmia Journal medical science, Vol. 9, No. 3, Autumn 1998, pp. 168-162 14- Behnam B,Taheri R,Sadat Hashemi M,Nesari-Rad Motlagh M.frequency of psychopathological manifestations in psoriatic patients in semnan city , central part of iran.Journal of Fundamentals of Mental Health, Autumn,2010,Vol.12,No.3(47),P.604-11. 15- Gul . EXPERIENCE OF ANXIETY AND DEPRESSION AMONG PSORIASIS PATIENTS. ASIAN JOURNAL OF SOCIAL SCIENCES & HUMANITIES .2102. Vol.1(4) - 051 061 16- Lakshmy S, Balasundaram S, Sarkar S, Audhya M, Subramaniam E. A Cross-sectional Study of Prevalence and Implications of Depression and Anxiety in Psoriasis. Indian J Psychol Med. 2015 Oct-Dec;37(4):434-40. 17- Cohen BE, Martires KJ, Ho RS. Psoriasis and the Risk of Depression in the US Population: National Health and Nutrition Examination Survey 2009-2012. JAMA Dermatol. 2016 Jan;152(1):73-9. doi: 10.1001/jamadermatol.2015.3605. 18- Tee SI, Lim ZV, Theng CT, Chan KL, Giam YC. A prospective cross-sectional study of anxiety and depression in patients with psoriasis in Singapore. J Eur Acad Dermatol Venereol. 2016 Mar 30. doi: 10.1111/jdv.13615. [Epub ahead of print] 19- Beck, A.T., Steer, R.A. & Garbin, M.G. Psychometric properties of the Beck Depression Inventory: Twenty-five years of evaluation. Clinical Psychology Review, 1988, 8, 77-100. 20- AzKhosh M. The use of psychological tests and clinical diagnosis. Psychotherapy, 2008; 3: 226-224

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