:: Volume 3, Issue 2 (June 2014) ::
Int J Med Invest 2014, 3(2): 0-0 Back to browse issues page
ESOPHASIAL MELANOSIS
Anahita Nosrati , Zhila Torabizadeh * , Shadi Tahvildari , Milad Bahari
Associate professor, department of pathology, Imam Hospital , Mazandaran University of Medical Science, Sari, Iran Medical Science, Sari, Iran.
Abstract:   (10932 Views)
Esophageal melanosis is a benign clinicopathologic diagnosis which it has been said more common in Asian than western population. In this entity melanin deposition in mucosa with an increased melanocytic proliferation can be realized . Its etiology is unknown but it is doubtful to be one of the precursors of esophageal melanoma . We aimed to represent and review histopathologic features of a case of melanosis. A 80 year old woman with long time history of dyspepsia referred to endoscopy department. There was a past history of reflux disease that under histopathologic evaluation and immunohistochemical staining it turned out to be brownish melanocyte proliferation Esophageal melanosis is a rare benign histopathologic lesion and it has been suggested as a melanoma precursor. Thus, making an accurate diagnosis and patient follow up are recommended.
Keywords: Esophagus, Melanocyte, Melanosis, IHC, HMB45, S100.
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Type of Study: case report | Subject: General


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Volume 3, Issue 2 (June 2014) Back to browse issues page