[Home ] [Archive]    
:: Main About journal Editorial Board Current Issue Archive Submit an article Site Map Contact ::
Main Menu
Home::
Journal Information::
Articles archive::
For Authors::
For Reviewers::
Registration::
Contact us::
Site Facilities::
Editorial Board::
::
Search in website

Advanced Search
..
Receive site information
Enter your Email in the following box to receive the site news and information.
..
:: Volume 11, Issue 2 (7-2022) ::
Int J Med Invest 2022, 11(2): 45-49 Back to browse issues page
Colistin Resistance: Critical Review of The literature
Sana Yahyazadeh Jasour , Zahra Fekrirad *
Department of Biology, Faculty of Basic Sciences, Shahed University, Tehran, Iran
Abstract:   (1464 Views)
Background: With the emergence of nosocomial pathogens and the emergence of Multidrug Resistant Microorganisms, continuous and intensive studies on changes in resistance patterns of clinic isolated bacteria seem necessary. Colistin sulfate is known to be the last line of treatment against the different range of antibiotic resistance. Recent evidences confirm emergence of the colistin resistance in various bacteria which should be examined and considered.
Methods: A critical review of the literature. 
Results: colistin as a member of earlier classis of antibiotics was still working against extended spectrum beta-lactamase-producing bacteria in last decades. This feature of the colistin was affiliated to its infrequent use due to fear of its medical adverse events. Meanwhile, recent reports indicate appearance of the colistin resistance in E. Coli, Acinetobacter baumannii and Klebsiella pneumoniae isolates. Sets of different genes in relation to the colistin resistance are proposed in literature. Efflux pumps might also play important role in appearance of these resistant strains.
Conclusion: When any other antibiotic does not work, Colistin is used as the last effective and Available treatment option for patients in treating patients. Because colistin is used in the last line of treatment, increasing resistance to it is a wake-up call for health systems.
 
Keywords: Acinetobacter Baumannii, Antibacterial Resistance, E. Coli, Colistin, Klebsiella Pneumoniae
Full-Text [PDF 204 kb]   (1157 Downloads)    
Type of Study: Review | Subject: General
Add your comments about this article
Your username or Email:

CAPTCHA


XML     Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Jasour S Y, Fekrirad Z. Colistin Resistance: Critical Review of The literature. Int J Med Invest 2022; 11 (2) :45-49
URL: http://intjmi.com/article-1-799-en.html


Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Volume 11, Issue 2 (7-2022) Back to browse issues page
International Journal of Medical Investigation
Persian site map - English site map - Created in 0.06 seconds with 37 queries by YEKTAWEB 4645