@ARTICLE{Rad, author = {Rad, Peyman and Taziki, Sadegh Ali and }, title = {Evaluating The Relationship Between The Severity Of Psoriasis And The Prevalence Of Depression In Patients With Psoriasis Compared With Healthy Subjects Referred To Dermatology Clinics Of Gorgan In 2016-17}, volume = {7}, number = {3}, abstract ={Introduction: Psoriasis is a systemic inflammatory disease and the most common recurrent chronic skin disease which affects almost 2% of the population and may occur at any age. This chronic disease causes changes in the appearance that impairs the patients’ mental image of themselves and causes rejection from society, isolation, personality disorders, depression, low self-esteem and weakened position of the person in the family. Due to the lack of permanent recovery of patients with medications, psychiatric interventions lead to improvements in the quality of life in these patients. An accurate assessment of the relationship between disease severity and psychopathology of it hasn’t been done in our society, so we decided to assess the relationship between disease severity and depression rate in patients with psoriasis referred to dermatology clinics is Gorgan in 2016-17 compared to healthy subjects. Method : In this case-control study, 68 patients with psoriasis referred to dermatology clinics in Gorgan in 1395 and 68 normal controls were examined for depression using standard Beck (Beck II ) test. Severity of the disease was calculated based on Psoriasis Area Severity Index Score (PASI Score). The data gathered was analyzed using statistical tests with confidence level of 0.95, and statistical power of 0.9 with SPSS software (version 18). Findings: This study evaluated 70 patients with psoriasis referred to dermatology clinics in Gorgan in 2016-17 and 70 healthy subjects as controls. In each group 22 subjects were male (31.4%) and 48 subjects were female (68.6%). Average disease severity was 35/17 ± 27 percent. With the increasing severity of psoriasis, the rate of depression is higher among patients. (P=0.0001) The rate of mild, moderate and severe depression in the case group was higher than the control group. This difference is statistically significant (p=0.0001) Conclusion: Depression symptoms are remarkably observed in psoriasis patients and the rate of these symptoms compared to healthy individuals is greater and these symptoms have a strong significant correlation with the severity of psoriasis. }, URL = {http://intjmi.com/article-1-334-en.html}, eprint = {http://intjmi.com/article-1-334-en.pdf}, journal = {International Journal of Medical Investigation}, doi = {}, year = {2018} }