%0 Journal Article %A Hassan Zadeh, Farhad %A Habibi Asl, Bohlool %T An Investigation In To the Effect of Buprenorphine Tablet on Drug Rehabilitation Clinics in Tabriz %J International Journal of Medical Investigation %V 8 %N 3 %U http://intjmi.com/article-1-425-en.html %R %D 2019 %K Addiction, Opium, Buprenorphine, %X Introduction: One of the typical ways of drug rehabilitation in Iran is the usage of Buprenorphine tablets in drug rehabilitation clinics under the supervision of Practitioner. As the Buprenorphine acts as partial agonists in opioid receptors of the body, thus this medicine is used as the preservative in the dependence on opioid substances and leads to the elimination of the symptoms of drug rehabilitation among people giving up the substances. The aim of this study is to examine the effect of Buprenorphine among the addicted people to opium with daily usage of less than 3 grams in drug rehabilitation clinics in Tabriz. Methods: This research is carried out as a field study in ten top drug rehabilitation clinics according to the protocol of Tabriz University of medical science. Among existing files in clinics, people with daily opium usage of 3 grams or less were investigated. Patients’ information was collected using questionnaires containing nineteen (19) items and analyzed by SPSS software version 19. Findings: Findings indicate that the age range of (30 to 40) and harsh job situation increase the risk of addiction to opium. No evidence of giving up opium usage in replacement of Buprenorphine was observed. Factors like marital status and smoking are among the risk factors of tendency towards drug. Conclusion: It seems that Buprenorphine tablets with dosage of 4 mg on daily basis are effective among opium-addicted people with less than 3 grams and could lead to eliminate the giving up symptoms and success of the treatment. As a preservative treatment, it also leads to more stability and coherence in the families and makes the people return to their jobs and society as well. %> http://intjmi.com/article-1-425-en.pdf %P 47-54 %& 47 %! %9 Research %L A-10-1-268 %+ Professor ,Department of Pharmacology, Faculty of Pharmacy ,University of Tabriz, , Tabriz, Iran. %G eng %@ 2322-2913 %[ 2019