en عمومى General پژوهشي Research There is a recent study of the history of the pigmentary tumors. However, it does not mention brain metastases. Accordingly, extensive search of the Transactions of the Pathological Society of London, which I have in my mini-Library, was undertaken. Consequently, the findings are analysed here. They range not only from observing the brain in its “natural” state but also to abstracting useful data. In this context, some eponymous giants were exemplified in terms of anatomical exactitude. Even the concept of “emboli” appeared. Melanoma, Spread, Emboli, Brain, History 128 132 http://intjmi.com/browse.php?a_code=A-10-1-162&slc_lang=en&sid=1 Wilson I. B. Onuigbo 10031947532846002728 10031947532846002728 Yes Department of Pathology, Medical Foundation and Clinic, 8 Nsukka Lane, Enugu 40001, Nigeria.