en عمومى General گزارش مورد case report Malignant peripheral nerve sheath tumors are one of the rare soft tissue sarcomas, which have not good prognosis despite of treatments. In this paper we tend to report a malignant peripheral nerve sheath tumor in the legs of a 44-year-old patient with neurofibromatosis type Ι. The patient underwent surgical operation and chemotherapy, but unfortunately died due to lung metastatic involvement several years later. Despite the poor prognosis of the disease, early diagnosis can reduce mortalityand morbidity Malignant, Neurofibromatosis, Peripheral nerve sheath tumor 0 0 http://intjmi.com/browse.php?a_code=A-10-1-22&slc_lang=en&sid=1 Mehrdad Taghipour 1003194753284600599 1003194753284600599 Yes Baghiatollah University of Medical Sciences, Tehran, Iran Alireza Ahmadi 1003194753284600600 1003194753284600600 No Subspecialist of Hematology and Oncology, Hamedan University of Medical Sciences, Hamedan, Iran Mohammad Amin Fereydouni 1003194753284600601 1003194753284600601 No Student Research committee, School of Medicine, Hamedan University of Medical Sciences, Hamedan, Iran Moghadaseh Shams 1003194753284600602 1003194753284600602 No Resident of Radiology, Shahid Beheshti University of Medical Sciences, Tehran, Iran Niusha Nobari 1003194753284600603 1003194753284600603 No Student Research committee, School of Medicine, Hamedan University of Medical Sciences, Hamedan, Iran Lotfollah Davoudi 1003194753284600604 1003194753284600604 No Microbial Resistance Research Center, Mazandaran University of Medical Sciences, Sari, Iran Reza Maleki Gorji 1003194753284600605 1003194753284600605 No Microbial Resistance Research Center, Mazandaran University of Medical Sciences, Sari, Iran