International Journal of Medical Investigation
Int J Med Invest
Medical Sciences
http://intjmi.com
1
admin
2322-2913
2345-640x
no
no
14
8888
13
en
jalali
1393
12
1
gregorian
2015
3
1
4
1
online
1
fulltext
en
The Prevalence and Correlates of Pulmonary Hypertension in End Stage Renal Disease
عمومى
General
پژوهشي
Research
Abstract Objective To evaluate the incidence of unexplained pulmonary hypertension (PH) in end- stage renal disease (ESRD) and to evaluate its possible relationship with some clinical and biochemical parameters. Patients and Methods This study was conducted retrospectively at Prince Rashed Hospital (PRH), North of Jordan, on patients undergoing maintenance hemodialysis (HD) during August 2009 to August 2010.Demographic and clinical data were obtained from charts review and Patients themselves. 2Dimensional echocardiography (2DECHO) was performed in all patients. Blood samples were taken for parathormone (PTH) and other biochemical measurements. SPSS package was used for statistical analysis.Statistical significance was considered at p value < 0.05. Results A total of 131 hemodialysis (HD) patients were included in the study, of them 76 (58, 9%) were men. The mean age of the study population was 53.7 + 16.2 yrs. Pulmonary hypertension (pulmonary artery pressure (PAP)=47+3, range 35-79mmHg) was detected in 52 patients (39.6%).The levels of PAP were positively correlated with serum intact parathormone (iPTH) levels, age, duration of HD, mean arterial pressure (MAP), interventricular septal (IVS) thickness, cardiac output(CO), and serum levels of phosphorus , creatinine, whereas the levels of PAP were inversely correlated with the levels of serum calcium and hemoglobin(Hb). Conclusion Pulmonary hypertension is a frequent finding in end stage renal disease and mineral disorders together with secondary hyperparathyroidism (SHPTH), increased cardiac output and anemia may be involved in the pathogenesis of this abnormality. The early detection and treatment of pulmonary hypertension aiming to decrease its serious complications is mandatory.
Pulmonary hypertension, mineral metabolism, echocardiography, end- stage renal disease. Prince Rashed Hospital.
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http://intjmi.com/browse.php?a_code=A-10-1-73&slc_lang=en&sid=1
Mohammed
Al-Jamal
10031947532846002419
10031947532846002419
No
Specialist of general medicine, Royal Medical Services , Amman, Jordan.
Quteiba
Nuseir
10031947532846002420
10031947532846002420
Yes
Specialist of general medicine, Royal Medical Services , Amman, Jordan.
Omar
Odat
10031947532846002421
10031947532846002421
No
Cardiologist, , Royal Medical Services , Amman, Jordan
Faraj
Al-hazaymeh
10031947532846002422
10031947532846002422
No
Specialist of general medicine, Royal Medical Services , Amman, Jordan.
Atef
Hattab
10031947532846002423
10031947532846002423
No
Specialist of general medicine, Royal Medical Services , Amman, Jordan.