eng
International Journal of Medical Investigation
International Journal of Medical Investigation
2322-2913
2345-640x
2016-06
5
2
36
40
article
Controversy Concerning Constitutional Cancer: Historical Review
Wilson I. B. Onuigbo
1
Department of Pathology, Medical Foundation and Clinic, 8 Nsukka Lane, Enugu 40001, Nigeria
Abstract
Objective: The general pathology of cancer was long in turmoil over the two extremes of constitutionalism and localism. Therefore, my mini-Library of historical works was searched so as to obtain a good idea as to the ultimate development.
Methods: Many different literatures on the subject matter were reviewed and used.
Results: Two major issues were delineated. The constitutional theory saw cancer being a whole body affair with some local manifestations whereas the localists believed in a focal origin which may go on to manifest widely. Naturally, there was the midway group called the dualists who managed to hold both concepts
Conclusion: The controversy that reigned in the history of these concepts are deemed to be worthy of documentation. By 1900, the localists gained the upper hand principally on the principle of embolism.
http://intjmi.com/article-1-223-en.pdf
Cancer
Constitutionalists
Dualists
Localists
Embolism
History
eng
International Journal of Medical Investigation
International Journal of Medical Investigation
2322-2913
2345-640x
2016-06
5
2
41
47
article
Illness behaviour: normal to abnormal- a selective systematic review of research from india
Geetha Desai
1
Gayatri Saraf
2
Santosh K Chaturvedi
3
Department of Psychiatry, NIMHANS, Bangalore, India
Senior Resident, Bhopal Memorial Hospital and Research Centre, Bhopal, India
FRCPsych, Professor, Department of Psychiatry, NIMHANS, Bangalore, India
Abstract
Objective: Illness behaviour is an important concept studied across various medical conditions. It determines the ways person respond and react to their health status and has significant impact on the health systems and individual. However, there are no systematic reviews on this important topic. To do a selective systematic review of researches done in India on illness behaviours across different health conditions.
Methods: Journal articles were identified through search on the PubMed, Medline, PsychInfo electronic databases from 1970 to 2015 with the search terms (Illness behaviour, India, Abnormal illness behaviour). The full articles were reviewed to identify measures used and important findings were extracted and summarised.
Results: There were 15 studies which were based on patients and two review articles (non-systematic). The studies on illness behaviour focused on somatoform disorders, tuberculosis and stroke. Scales used for assessment included Illness Behaviour Questionnaire (IBQ), Illness Behaviour Assessment Schedule (IBAS) and Screening for Illness Behaviour Questionnaire (SIBQ). No studies were found on intervention for abnormal illness behaviour.
Conclusion: Illness behaviours are an important aspect of somatoform disorders. It is difficult to draw conclusions due to relatively small number of studies. More studies including randomised control designs are needed to understand patterns of illness behaviour across disorders.
http://intjmi.com/article-1-224-en.pdf
Illness behaviour
somatoform disorders
multiple somatic complaints
systematic review
India.
eng
International Journal of Medical Investigation
International Journal of Medical Investigation
2322-2913
2345-640x
2016-06
5
2
50
53
article
Histopathologic discrepancy between prostatic core biopsy and open radical prostatectomy specimens in clinically localized prostatic cancer
Abdullah Rababaah
1
Mohammad Alserhan
2
Ahmad Alhiari
3
Laith Khasawneh
4
Nizar Saaideh
5
Omer Alshokhaibi
6
Specialist in Labaratory and Histopathology, Jordan Royal medical services
Specialist in Labaratory and Histopathology, Jordan Royal medical services
Specialist in Labaratory and Histopathology, Jordan Royal medical services
Specialist in Labaratory and Histopathology, Jordan Royal medical services
Specialist in Labaratory and Histopathology, Jordan Royal medical services
Specialist in Labaratory and Histopathology, Jordan Royal medical services
Objective: 1. To assess the histopathologic discrepancy between prostatic needle biopsy and open radical prostatectomy specimens in terms of Gleason score upgrading and bilaterality
2. To evaluate the impact of this discrepancy on the surgical margin status of radical prostatectomy specimens Methods: This study was conducted at Prince Hussein Urology Center, Amman, Jordan. Between May 2010 and August 2015, 74 patients underwent open radical prostatectomy for localized prostatic cancer diagnosed by prostatic needle biopsy based on high PSA level. We compared histopathologic findings regarding Gleason score and bilaterality between prostatic biopsy and radical prostatectomy specimens, and then we evaluated the impact discrepancy between them on the surgical margin status of radical prostatectomy specimens.
Results: 52 patients (70%) had upgrade in Gleason score with mean increase by one. All 34 patients who had bilateral disease on prostatic biopsy had bilateral disease on radical prostatectomy, but of the remaining 40 patients with unilateral disease 18 patients (45%) had bilateral disease on radical prostatectomy specimen. Surgical margin was involved in 3 patients (4%), all of them had Gleason score > 7 and bilateral disease on both biopsy and surgical specimens.
Conclusion: In spite of the significant histopathologic discrepancy between prostatic needle biopsy and open radical prostatectomy specimens, however in clinically localized prostatic cancer this discrepancy has no impact on surgical margin status.
http://intjmi.com/article-1-226-en.pdf
Histopathologic
radical prostatectomy
cancer
eng
International Journal of Medical Investigation
International Journal of Medical Investigation
2322-2913
2345-640x
2016-06
5
2
54
59
article
The Effect of Music Therapy on the Vital Signs of Patients in a Surgical Intensive Care Unit
Seyhan Çıtlık Sarıtaş
1
Bilsev Araç
2
Inonu University, Nursing Department, Faculty of Health Sciences, 44280, Malatya, Turkey
Inonu University Institute of Health Science, Malatya, Turkey
Objective: The purpose of this study is to examine the effect of musicotherapy on the vital signs of patients in a surgical intensive care unit.
Methods: This quasi-experimental research was conducted at Inonu University Turgut Ozal Medical Center General Surgery Intensive Care Unit (ICU). The study population consisted of patients who had been hospitalized in the ICU during the last 24 hours, who remained at least one day in the ICU, and who agreed to participate in the study. They were over 18 years of age, and their levels of consciousness were 5 or higher according to the Glasgow Coma Scoring System. The sample was collected from 202 patients who were hospitalized at TOTM general surgery ICU after power analysis. Patient identification forms and the registration forms containing vital signs before and after the intervention were used for data collection. Information from patient identification forms and registration forms indicating vital signs (pulse rate, systolic and diastolic blood pressure, oxygen saturation level) before music therapy was recorded on the second day after admission to general surgery ICU. This information about the patients was recorded again after music therapy. The data were evaluated with descriptive statistics and a paired t test.
Results: Pulse rates, systolic and diastolic blood pressures were lowered by music therapy, and low oxygen saturations were raised by music therapy.
Conclusion: The results show that music therapy is effective.
http://intjmi.com/article-1-227-en.pdf
ICU
Music therapy
Vital signs
Nursing intervention.
eng
International Journal of Medical Investigation
International Journal of Medical Investigation
2322-2913
2345-640x
2016-06
5
2
60
64
article
Compare the Magnetic Resonance Imaging (MRI) and conventional radiography in diagnosis of distal radius injury before skeletal maturity
Seyyed Mehran Razavipour
1
Roohollah Abdi
2
Mehran Fazli
3
Saeed Ghorbani
4
Assistant Professor, Department of orthopedics, Imam Khomeini Hospital, Mazandaran University of medical science, Sari, Iran
Department of Radiology, Mazandaran University of medical science, Imam-Khomeini Hospital, Sari, Iran
General Practitioner in Imam Khomeini Hospital of Esfarayen, Esfarayen Faculty of Medical Sciences, Esfarayen, Iran
Department of Radiology, Mazandaran University of medical science, Imam-Khomeini Hospital, Sari, Iran
Objective: Physeal injuries in childhood may produce irreversible damage to the growing cells, resulting in growth disturbance. The aim of this study is compare conventional radiography and magnetic resonance imaging (MRI) in the assessment of distal radius epiphyseal and physeal injury.
Methods: 31 cases with distal radius trauma were examined with conventional radiography and MRI. One blinded experienced radiologists and one blinded experienced specialist in orthopedics separately evaluated the results.
Results: The main age of our patient was 11.74±2.98 years. The results of MRI showed 90.32% injury in all patients whiles conventional radiography showed 64.51% injuries (P=0.014). In survey the physeal injury by conventional radiography we have 6 Salter–Harris II fractures. Meanwhile, the MRI showed 9 physeal injuries that included 6 Salter–Harris II fracture and 3 other fracture with physeal injury (all of them had distal radius microfracture with mild physeal injury) (P>0.05). In patients that conventional radiography showed they were normally, MRI showed 4 Bone Bruising and 4 microfracture. The other results were similar. The sensitivity, specificity, Positive predictive value, negative predictive value and total accuracy of conventional radiography in diagnosis of physeal injury were 66.6%, 100%, 100%, 88%, 90.32%.
Conclusion: our study showed MRI and conventional radiography had almost similar power to diagnosis growth plate injuries in distal radius trauma. When we considering high cost of MRI, it’s seems that conventional radiography was beneficial than MRI to use in distal radius injury.
http://intjmi.com/article-1-228-en.pdf
Magnetic Resonance Imaging
Physis
Radius Fractures
Radiography
eng
International Journal of Medical Investigation
International Journal of Medical Investigation
2322-2913
2345-640x
2016-06
5
2
65
68
article
Evaluation of Self-Immolation Suicide attempt in Sari City (north of Iran) between 2011 to 2014
Seyed Hamzeh Hosseini
1
Fatemeh Yazdanpanah
2
Hossein Ali Ghannadzadegan
3
Mehran Fazli
4
Psychiatry Research Center, School of Medicine, Mazandaran University of Medical Sciences, Sari, Iran
Department of psychology, Sari Branch, Islamic Azad University, Sari, Iran
Department of psychology, Sari Branch, Islamic Azad University, Sari, Iran
General Practitioner in Imam Khomeini Hospital of Esfarayen, Esfarayen Faculty of Medical Science, Esfarayen, Iran
Abstract
Objective: Self-immolation is one of the terrible way of suicide. Lack of data about suicide by Self-immolation method in Sari city (north of Iran) caused we designed this study to evaluation of self-immolation suicide attempt in Sari City (north of Iran) between 2011 to 2014.
Methods: In a retrospective study we review the medical record of 74 cases that attempt to suicide by self-immolation between 2011 and 2014 in Sari City (North of Iran). The medical record of all these patients included age, sex, marital status, residency in urban or rural, the season in which they attempt suicide, length of hospital stay, history of psychiatric diseases, history of underling disease, history of addiction and results of suicide attempt were collected. Data was analyzed by SPSS version 18.
Results: 74 patients included 52 females (70.3%) were attempt suicide by self-immolation method. The female to male ratio was 2.36. the mean age of all patients was 32.32±12.89 years old (between 12 to 75 years). There was no significant difference between mean age of women and men (32.55±13.64 vs. 31.77±11.20 years respectively, P=0.81). the prevalence of self-immolation was higher in spring (36.5%). Majority of the cases were married (59.5%). 19 patients (25.7%) was addicted to drugs included 16 opium addiction (84.2%) and 5 crack addiction (15.8%). 25 cases (33.8%) had history of psychiatric disease and 13 cases (17.6%) had history of seizure. Finally, 68 cases (91.9%) from 74 patents were die.
Conclusion: The prevalence of self-immolation was higher in women, spring, between drug user and in married patients. Suicide by self-immolation was associated with high rate of mortality.
http://intjmi.com/article-1-229-en.pdf
Self-Immolation
Suicide
Suicide attempt
eng
International Journal of Medical Investigation
International Journal of Medical Investigation
2322-2913
2345-640x
2016-06
5
2
69
72
article
Case report: A 27 years old woman with brain metastases of synovial sarcoma
Anahita Nosrati
1
Sajad Shafiee
2
Emadi Aazam
3
Department of pathology, Gastrointestinal cancer register center, Imam Khomeini hospital, Mazandaran university of medical sciences,Sari,Iran
Department of neurosurgery, Imam Khomeini hospital, Mazandaran university of medical sciences .Sari, Iran.
Department of pathology, Imam Khomeini hospital, Mazandaran university of medical sciences. , Sari, Iran
A 27- year old lady with severe headache, nausea, vomiting and impaired cerebellar function. She had a history of a left arm synovial sarcoma and she was evaluated with magnetic resonance imaging (MRI) that shows a gadolinium enhanced mass measuring about 7 mm in diameter with both solid and cystic portions in left cerebellar hemisphere causing mass effect. Histologic evaluation confirmed poorly differentiated type synovial sarcoma composed of tumor cells containing pleomorphic round to oval hyper chromatic to vesicular nuclei with coarse chromatin and a little light eosinophilic cytoplasm. The IHC stain is done and showed EMA, CK and vimentin positivity in tumor cells. The patient was treated with surgery, chemotherapy and radiotherapy. In the follow up study at 6 month post chemotherapy evaluation computed tomography (CT scan) showed pulmonary metastases and transthoracic biopsy revealed the same pathologic feature. According to our patient, brain metastasis could occur even in extremities synovial sarcoma and so CNS imaging as screening may be introduced in follow up plan of these patients.
http://intjmi.com/article-1-230-en.pdf
synovial sarcoma
brain metastases
pulmonary metastases.
eng
International Journal of Medical Investigation
International Journal of Medical Investigation
2322-2913
2345-640x
2016-06
5
2
73
75
article
Pilomatrix carcinoma of face a case report
Hayat AL-Khasawneh
1
Shefaa Al-Mashagbah
2
Deifallah AL-Sharari
3
Olaa AL-Waqfi
4
Jehad AL-Assaf
5
King Hussein Medical Center, Amman,Jordan
King Hussein Medical Center, Amman,Jordan
King Hussein Medical Center, Amman,Jordan
King Hussein Medical Center, Amman,Jordan
King Hussein Medical Center, Amman,Jordan
Pilomatrix carcinoma is an exceedingly rare malignant tumor derived from hair follicle. Although it has been described at various anatomical sites, fewer than 25 cases have been reported in the face and scalp. The diagnosis of pilomatrix carcinoma is based on histological examination of skin biopsy. . We report a case of pilomatrix carcinoma in an 85 year old male patient presented with cheek nodule.
http://intjmi.com/article-1-231-en.pdf
pilomatrix carcinoma