Volume 12, Issue 1 (3-2023)
J Emerg Health Care 2023, 12(1): 54-58 |
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Assistant professor. Department of Anesthesiology, Anesthesiology, Critical Care and Pain Management Research Center, Faculty of Medicine, Hormozgan University of Medical Sciences, Bandar Abbas, Iran
Abstract: (3038 Views)
Background:
This study aimed at comparing mortality and morbidity in TBI patients, with and without ICP monitoring.
Method: This study was designed as a retrospective case-control study. The study compared mortality and morbidity (bleeding and meningitis) outcomes, length of hospitalization, and trends of Glasco coma scale changes in patients who underwent ICP monitoring (case group, n=11) with non-monitored (control group, n=11) patients. These subjects were matched for age and sex.
Results: Groups were matched for age and demographic variables (P>0.05). However, initial GCS in case group was significantly lower than controls (P=0.009). So assuming that this variable is a confounding factor, other comparisons were made by adjusting the initial GCS. ICP monitoring had a statistical association with mortality (OR= 22.80, 95% CI: 2.28-227.76; p<0.0001), but not with meningitis. After adjusting for baseline GCS, there were no differences between adjusted and non-adjusted results; but small sample size restricts this statement. The adjusted means of GCS on day 1 for case group and control group were 9.04 and 12.44, respectively (p=0.045). The adjusted means of GCS on day 2 for case group and control group were 10.27 and 13.23, respectively (p=0.073).
Conclusion: The retrospective case control design failed to assess the hypothesis of associations between ICP monitoring and outcomes of TBI, in our small sample size study.
This study aimed at comparing mortality and morbidity in TBI patients, with and without ICP monitoring.
Method: This study was designed as a retrospective case-control study. The study compared mortality and morbidity (bleeding and meningitis) outcomes, length of hospitalization, and trends of Glasco coma scale changes in patients who underwent ICP monitoring (case group, n=11) with non-monitored (control group, n=11) patients. These subjects were matched for age and sex.
Results: Groups were matched for age and demographic variables (P>0.05). However, initial GCS in case group was significantly lower than controls (P=0.009). So assuming that this variable is a confounding factor, other comparisons were made by adjusting the initial GCS. ICP monitoring had a statistical association with mortality (OR= 22.80, 95% CI: 2.28-227.76; p<0.0001), but not with meningitis. After adjusting for baseline GCS, there were no differences between adjusted and non-adjusted results; but small sample size restricts this statement. The adjusted means of GCS on day 1 for case group and control group were 9.04 and 12.44, respectively (p=0.045). The adjusted means of GCS on day 2 for case group and control group were 10.27 and 13.23, respectively (p=0.073).
Conclusion: The retrospective case control design failed to assess the hypothesis of associations between ICP monitoring and outcomes of TBI, in our small sample size study.
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