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Trace elements also known as trace minerals, are the chemical components that naturally occur in soil, plant, and wildlife in minute concentrations. They are necessary for the optimal development and metabolic functioning such as proper cell metabolism, effective immune function, and healthy reproduction of humans . Their role and homeostasis in living organisms varies. There are 19 known trace elements that are categorized in three groups (WHO classification) essential elements ,probably essential elements, and potentially toxic elements .This review provides some detailed information and criteria for assessing the probable trace element status in human physiology . In addition, for some elements it may offer additional effective ways of diagnosis to physicians as well as interested peoples.

     

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