[Home ] [Archive]    
:: Main About journal Editorial Board Current Issue Archive Submit an article Site Map Contact ::
:: Volume 10, Issue 3 (9-2021) ::
Int J Med Invest 2021, 10(3): 0-0 Back to browse issues page
Does Gabapentin Decrease Post-Mastectomy Acute and Chronic Pain? A Systematic Review of Clinical Trials
Mansour Rezaee, Ahmad Sheikhloo, Ali Reza Naseri *
3. Department of radiation-oncology, School of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran.
Abstract:   (151 Views)
Introduction: Mastectomy is associated with moderate to severe pain. Researchers are recently exploring new modalities and drugs to avoid numerous side effects associated with prescribed narcotics. For treatment, gabapentin is a widely used medication, but there is no comprehensive report on the post-mastectomy effects of this medication. Thus, this study aims to evaluate the effects of gabapentin on managing acute pain after surgery.
Methods: This was a systematic review (PRISMA checklist) study in which clinical trial articles published between 2000-2020 using the Cochrane checklist in PubMed, OVID, Medline, Scopus, Web Of Science with breast keywords cancer, gabapentin, postoperative pain, mastectomy, breast surgery, postoperative analgesia, ERAS, multimodal therapy were sought to evaluate the effect of gabapentin on post-mastectomy pain.
Results: In the initial search, 288 articles were found. Twenty-one articles were ultimately selected by repeated trading off, including reviewing texts and abstracts, outcomes, results, and the general conclusion, and included in this meta-analysis; The results of most studies have shown that gabaanthin can lead to Acute and Chronic Pain Decrease Post-Mastectomy. Gabapantin also reduced the need for drugs to control pain.
Conclusion: Dispensing gabapentin as a single treatment or in combination with other therapies meaningfully alleviates pain and diminishes drug use after breast surgery.
Keywords: Breast cancer, Mastectomy, Pain, Gabapentin
     
Type of Study: Research | Subject: General
Add your comments about this article
Your username or Email:

CAPTCHA


XML     Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Rezaee M, Sheikhloo A, Naseri A R. Does Gabapentin Decrease Post-Mastectomy Acute and Chronic Pain? A Systematic Review of Clinical Trials. Int J Med Invest. 2021; 10 (3)
URL: http://intjmi.com/article-1-648-en.html


Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Volume 10, Issue 3 (9-2021) Back to browse issues page
International Journal of Medical Investigation
Persian site map - English site map - Created in 0.04 seconds with 29 queries by YEKTAWEB 4331