[Home ] [Archive]    
:: Main About journal Editorial Board Current Issue Archive Submit an article Site Map Contact ::
:: Volume 11, Issue 3 (10-2022) ::
Int J Med Invest 2022, 11(3): 0-0 Back to browse issues page
The Role Inflammation In Dental Caries Repair
Mahsa Farshbaf Antic *
Department of Operative Dentistry, Faculty of Dentistry, Tabriz University of Medical Sciences, Tabriz, Iran
Abstract:   (194 Views)
Dental caries is being considered as the most common noncommunicable disease worldwide. It is being defined as sugar-driven, biofilm mediated and dynamic disorder which causes remineralization and demineralization of teeth hard tissues involving inflammatory system. It has been shown that IL-6, IL-8 and TNF-a was signifncatly increased in saliva of patients with dental caries. A cascade of four steps is required to repair dental pulp by direct capping with calcium hydroxide or by implanting bioactive extracellular matrix molecules: moderate inflammation, commitment of adult reserve stem cells, proliferation, and differentiation of these cells. Osteoblast/odontoblast-like differentiation and expression of mineralization-related ECM molecules may also be promoted by mild inflammation of antigen-presenting dendritic cells. Studies in humans and in vitro indicate that dentin barrier formation occurs only when pulp inflammation and infection are minimized, allowing for tissue homeostasis to return. To ensure the sustainability of dental treatments, promoting the resolution of pulp inflammation may be a valuable therapeutic opportunity. We have reviewed the role inflammation in caries repair in this study.
Type of Study: Review | Subject: General
Add your comments about this article
Your username or Email:


XML     Print

Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Antic M F. The Role Inflammation In Dental Caries Repair. Int J Med Invest. 2022; 11 (3)
URL: http://intjmi.com/article-1-847-en.html

Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Volume 11, Issue 3 (10-2022) Back to browse issues page
International Journal of Medical Investigation
Persian site map - English site map - Created in 0.05 seconds with 30 queries by YEKTAWEB 4463