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Association Of Coronary Artery Disease With Psoriasis In A Group Of Patients In Queen Alia Heart Institute (Qahi) In Jordan
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Ramzi A .Hiary *   , Ashraf H. Qubbaj , Ahmad A. Rababa , Jehad Sh. Al-Asssaf |
| Cardiologist at qahi (amman –jordan) |
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Abstract: (7432 Views) |
| Objective: The aim of our study is to demonstrate the association between psoriasis and CAD in a group of patients at QUEEN ALIA HEART INSTITUTE (QAHI). Methods: This retrospective study was conducted at QUEEN ALIA HEART INSTITUTE from April 2012 to August 2016. 167 psoriatic patients (with moderate to severe psoriasis) and 197 non-psoriatic patients (control group) were matched by sex, age and risk factors of CAD. All patients underwent coronary angiography, and the incidence of coronary artery disease was compared between the two groups. Results: After analysis, the p-value of CAD risk factors in both groups (psoriasis and controls) were: age (41.3 year, 35.4 ,0.04) , male (67% , 64% ,0.06), smoking (60.5% , 56% , 0.4) , HTN (40.5 % , 43% , 0.29 ) ,DM (37.5% ,36.3% ,0.3), hyperlipidemia (20.3% , 17.8% , 0.41), family history (36.1% ,34..4 ,0.05). After matching for all these risk factors, the rate of CAD in psoriasis patients was (8.2%) and (2.1%) in non-psoriatic patients with p-value less than 0.001. Conclusion: Psoriasis (moderate and severe) is an independent risk factor for increasing the risk of coronary artery disease in (sex, age, and other risk factor for CAD) matched patients. |
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| Keywords: CORONARY, ARTERY, DISEASE |
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Type of Study: Research |
Subject:
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| References |
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1. 1. Lomholt G. Prevalence of skin disease in a population: A cencus study from the Faroe Islands .Dan Med Bull1964, 11:1-7
2. Psoriasis Update-skin &Aging Retrieved 2007- 07- 28.
3. Langley RG, Krueger GG, Griffiths CE. Psoriasis: epidemiology, clinical features, and quality of life. Ann Rheum Dis 2005 Mar, 64 Suppl 2:ii18-23
4. Krueger JG, Bowcock A. Psoriasis pathophysiology: current concepts of pathogenesis. Ann rheum Dis 2005 Mar, 64 suppl 2:ii30-6.
5. Gisondi P, Dalle VC, Girolomoni G. patients with psoriasis have a higher prevalence of parental cardiovascular disease. Dermatology 2011, 222(4):330-335
6. AL-Mutairi N, AL- Farag S, AL-Mutairi A, AL-Shiltawy M. Co morbidities associated with psoriasis an experience from the Middle East. J Dermatol 2010 Feb, 37(2):146-5
7. Ahlehoff O. Psoriasis and cardiovascular disease: epidemiological studies. Dan Med Bull 2011 Nov, 58(11):B4347
8. Puig-Sanz L. Psoriasis, a systemic disease? Actas Dermosifiliogr 2007 Jul-Aug,98(6):396-402.
9. Kimball AB, Robinson Jr D, Wu Y, et al Cardiovascular disease and risk factors among psoriasis patients in two US healthcare databases 2001-2002. Dermatology 2008, 217:27-37.
10. Lin HW, Wang KH, Lin HC, Lin HC. Increase risk of myocardial infarction in patients with psoriasis: a 5-year population-based study in Taiwan. J Am Acad Dermatol 2011 Mar, 64(3):495-501
11. Joel MG, Rahat SA, Nehal NM. Psoriasis and cardiovascular risk: strength in numbers. Journal of investigative Dermatology 2010, 130,919-922.
12. Robert SS. Psoriasis is not a useful independent risk factor for cardiovascular disease. Journal of Investigative Dermatology 2010, 130,917-919
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A .Hiary R, H. Qubbaj A, A. Rababa A, Sh. Al-Asssaf J. Association Of Coronary Artery Disease With Psoriasis In A Group Of Patients In Queen Alia Heart Institute (Qahi) In Jordan. Int J Med Invest 2017; 6 (1) :19-20 URL: http://intjmi.com/article-1-266-en.html
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