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:: Volume 8, Issue 2 (5-2019) ::
Int J Med Invest 2019, 8(2): 120-125 Back to browse issues page
Neurological Disorders due to Recurrent Hypoglycemia
Mazen Oudat *, Aktham Al Domour, Awni Al Shiab, Mohamad Al Adamat, Shahir Al Etan, Abed Rahim Al Dwarii
Neurologist and Internist at Royal Medical Services, King Hussein Hospital, Amman, Jordan.
Abstract:   (66 Views)
The most important material for the brain tissues is glucose .The brain utilizes around (25%) of the body's glucose, and it's metabolism thought to be primarily by astrocytes through non-insulin dependent (GLUT-1) transporter and insulin dependent (GLUT-4) transporter, but the brain contains very limited stores of glycogen, and therefore it can't regulate it's function for long time without glucose.
So neuronal damage can lead to multiple neurological manifestations as a result of hypoglycemia acutely; stroke like symptoms, movement disorders (tremor, ataxia, difficulty of walking), seizures, coma and death; chronically and repetitive leads to cognitive impairment. Which means clinical picture appears according to the area of neuronal damage.
Keywords: NMDA receptor: N-Methyl-D-Aspartate receptor, WM: White Matter, ischemia, neuronal DNA, Hypoxia, Basal ganglia, cerebral peduncle.
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Type of Study: Research | Subject: General
References
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Oudat M, Al Domour A, Al Shiab A, Al Adamat M, Al Etan S, Al Dwarii A R. Neurological Disorders due to Recurrent Hypoglycemia. Int J Med Invest. 2019; 8 (2) :120-125
URL: http://intjmi.com/article-1-407-en.html


Volume 8, Issue 2 (5-2019) Back to browse issues page
International Journal of Medical Investigation
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