The Pre Analytical Phase: Precautions in Specimen Collection and Patient Preparation  for  Trace and Ultra Trace Elements Analysis

Aliasgharpour, Mehri

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Volume 5, Issue 4 (12-2016)

Int J Med Invest 2016, 5(4): 138-139

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The Pre Analytical Phase: Precautions in Specimen Collection and Patient Preparation for Trace and Ultra Trace Elements Analysis

Mehri Aliasgharpour ^*

Clinical Biochemistry Faculty Member- Ministry of Health & Medical Education- Reference Health Laboratory Research Center,Tehran,Iran

Abstract: (13079 Views)

Pre analytical factors are probably the most important causes of erroneous trace element reference data in biological matrices today and the development of sensitive , specific, and accurate analytical technology at an acceptable cost has moved determination of trace and ultra trace elements from research facilities into a wide range of clinical laboratories. Besides, expanding knowledge of trace element nutrition and toxicity has increased clinical demand for these assays. However, with increased sensitivity and lower limits of detection the problem of specimen contamination with the element of interest has been magnified. It is vital that the accurately determined trace element concentration to reflect the condition of the patient and not contamination introduced during collection and handling. In the following paper, the concept of pre analytical factors that can contribute to trace and ultra trace elements concentration are discussed. In addition, specific percussions for collecting different sample types and special considerations in patient preparations and sample types for specific Trace and Ultra Trace Elements analysis are addressed.

Keywords: Trace Elements- Pre analytical Phase-Anticoagulated- Specimen collection

Full-Text [PDF 275 kb] (2552 Downloads)

Type of Study: Review | Subject: General

References

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Aliasgharpour M. The Pre Analytical Phase: Precautions in Specimen Collection and Patient Preparation for Trace and Ultra Trace Elements Analysis. Int J Med Invest 2016; 5 (4) :138-139
URL: http://intjmi.com/article-1-255-en.html

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