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:: Volume 4, Issue 1 (march 2015) ::
Int J Med Invest 2015, 4(1): 187-190 Back to browse issues page
Down syndrome Associated with Epstein’s Anomaly and Pulmonary Hypertension in a 2.5 Months Infant: a Case Report Study
Asadollah Tanasan , Farshad Rostampour * , Ahmad Jamei Khosroshahy , Milad Sanginabadi , Amin Falahi
2. General Practitioner, Sirvan Health Network, Ilam University of Medical Sciences and Health Services, Ilam, Iran
Abstract:   (11347 Views)
Abstract In children with Down syndrome (DS) there is higher chance for concomitant congenital heart defects and organic disorders. However Epstein’s anomaly is a rare association of DS. We report a 2.5 months DS boy that referred to our hospital with tachypnea. In echocardiography the septal leaflet displaced downwardly toward the apex about 8.2 mm and displacement index was 27.3 mm/m2, Tricuspid regurgitation (TR) was moderate (VC=5.5mm) with 70 mmHg gradient also an ASD with bidirectional shunt and a membranous VSD were seen. catheterisation and angiography was done, pulmonary arterial pressure was subsystemic and a 2.5 mm size PDA was seen, in the levophase a medium size VSD was seen. The patient is under follow up with lanoxin, captopril and lasix now. As mentioned earlier Epstein’s anomaly is rare and it prevalence is about 0.5% of CHDs although 50% of patients with DS have CHD but its association with Epstein’s anomaly is very rare.
Keywords: Down syndrome, Epstein anomaly, Pulmonary Hypertension, Congenital Heart Defect, Tricuspid regurgitation
Full-Text [PDF 426 kb]   (2715 Downloads)    
Type of Study: Research | Subject: General
References
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Tanasan A, Rostampour F, jamei Khosroshahy A, Sanginabadi M, Falahi A. Down syndrome Associated with Epstein’s Anomaly and Pulmonary Hypertension in a 2.5 Months Infant: a Case Report Study. Int J Med Invest 2015; 4 (1) :187-190
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Volume 4, Issue 1 (march 2015) Back to browse issues page
International Journal of Medical Investigation
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