Journal of Emergency Health Care
Formerly known as: International Journal of Medical Investigation
Volume 4, Issue 1 (march 2015)
J Emerg Health Care 2015, 4(1): 187-190 |
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Tanasan A, Rostampour F, jamei Khosroshahy A, Sanginabadi M, Falahi A. Down syndrome Associated with Epstein’s Anomaly and Pulmonary Hypertension in a 2.5 Months Infant: a Case Report Study. J Emerg Health Care 2015; 4 (1) :187-190
URL: http://intjmi.com/article-1-100-en.html
URL: http://intjmi.com/article-1-100-en.html
Asadollah Tanasan 
, Farshad Rostampour * , Ahmad Jamei Khosroshahy , Milad Sanginabadi , Amin Falahi
, Farshad Rostampour * , Ahmad Jamei Khosroshahy , Milad Sanginabadi , Amin Falahi
2. General Practitioner, Sirvan Health Network, Ilam University of Medical Sciences and Health Services, Ilam, Iran
Abstract: (11930 Views)
Abstract In children with Down syndrome (DS) there is higher chance for concomitant congenital heart defects and organic disorders. However Epstein’s anomaly is a rare association of DS. We report a 2.5 months DS boy that referred to our hospital with tachypnea. In echocardiography the septal leaflet displaced downwardly toward the apex about 8.2 mm and displacement index was 27.3 mm/m2, Tricuspid regurgitation (TR) was moderate (VC=5.5mm) with 70 mmHg gradient also an ASD with bidirectional shunt and a membranous VSD were seen. catheterisation and angiography was done, pulmonary arterial pressure was subsystemic and a 2.5 mm size PDA was seen, in the levophase a medium size VSD was seen. The patient is under follow up with lanoxin, captopril and lasix now. As mentioned earlier Epstein’s anomaly is rare and it prevalence is about 0.5% of CHDs although 50% of patients with DS have CHD but its association with Epstein’s anomaly is very rare.
Keywords: Down syndrome, Epstein anomaly, Pulmonary Hypertension, Congenital Heart Defect, Tricuspid regurgitation
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