The Prevalence of Depression in Multiple Sclerosis Patients Who Referred to the Multiple Sclerosis Society of Yazd, Iran

Hosseini, Fatemeh; Ayatollahi, Parisa; Behniafard, Nasim; Nadi, Mohammad; Shamsi, Farimah; Ferdousian, Amir Hossein

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Volume 4, Issue 3 (September 2015)

Int J Med Invest 2015, 4(3): 338-343

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The Prevalence of Depression in Multiple Sclerosis Patients Who Referred to the Multiple Sclerosis Society of Yazd, Iran

, Mohammad Nadi ^*

, Amir Hossein Ferdousian

Assistant Prof of Psychiatry, Department of Psychiatry, Shahid Sadoughi University of Medical Sciences, Yazd, Iran

Abstract: (10353 Views)

Abstract Background: Multiple sclerosis (MS) is a central nervous disease that may cause disability. Depression is very common in MS which has a negative impact on quality of life and cognitive status. This study was designed to determine the prevalence of depression in MS patients, to assess the association of neuropsychological, demographic factors and clinical features of it. Methods: This study was performed on 220 patients. A questionnaire was completed by patients and Beck Depression Inventory (BDI-II) test was used to evaluate the severity of depression. Results: 81.3% of patients had depression based on the cutoff point of 13. A significant relationship was found between gender, treatment duration, motion disability, Cerebellar and pyramidal symptoms and severity of depression,also between history of depression and prevalence of it. The prevalence of depression was more in age group of 20-40. No significant association was found between the duration of disease and severity of depression and demonstrated an inverse relationship between depression severity and level of education. Conclusion: We conclude, future studies should use a structured interview based on the DSM to assess patients' mood.

Keywords: Multiple sclerosis, prevalence, Depression, neuropsychological, interview

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Type of Study: Research | Subject: General

References

1. 1.Calabresi P.. In: . ed. Philadelphia Pc. Multiple sclerosis and demyelinating conditions of the central nervous system. In: Goldman L AD, eds. Cecil Medicine, editor. Cecil Medicine. 24 ed. Philadelphia, Pa: Saunders Elsevier; 2012. 2.Noseworthy JH, Lucchinetti C, Rodriguez M, Weinshenker BG. Multiple sclerosis. The New England journal of medicine. 2000;343 (13):938-52. 3.David A. Greenberg MJA, Roger P. Simon,. Clinical Neurology. 8, editor: McGraw Hill Professional, 2012. 400 pages p. 4.Elhami SR, Mohammad K, Sahraian MA, Eftekhar H. A 20-year incidence trend (1989-2008) and point prevalence (March 20, 2009) of multiple sclerosis in Tehran, Iran: a population-based study. Neuroepidemiology. 2011; 36 (3):141-7. 5.Etemadifar M, Maghzi AH. Sharp increase in the incidence and prevalence of multiple sclerosis in Isfahan, Iran. Multiple sclerosis (Houndmills, Basingstoke, England). 2011;17(8):1022-7. 6.Moghtaderi A, Rakhshanizadeh F, Shahraki-Ibrahimi S. Incidence and prevalence of multiple sclerosis in southeastern Iran. Clinical neurology and neurosurgery. 2013;115 (3):304-8. 7.Sahraian MA, Khorramnia S, Ebrahim MM, Moinfar Z, Lotfi J, Pakdaman H. Multiple sclerosis in Iran: a demographic study of 8,000 patients and changes over time. European neurology. 2010;64 (6):331-6. 8.Multiple sclerosis PubMed Health: U.S. National Library of Medicine; 2011. Available from: http://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0001747/#disclaimer. 9.Charcot JM. Lectures on the Diseases of the Nervous System: Delivered at la Salpêtrière: Henry C. Lea; 1879. 10.Butler MA, Bennett TL. In search of a conceptualization of multiple sclerosis: a historical perspective. Neuropsychology review. 2003;13 (2):93-112. 11.Mohr DC, Goodkin DE, Islar J, Hauser SL, Genain CP. Treatment of depression is associated with suppression of nonspecific and antigen-specific TH1 responses in multiple sclerosis. Archives of Neurology. 2001;58 (7):1081. 12. Multiple sclerosis Society of Canada Canada 2014.Available from: mssociety.ca/en/information/symptoms_mng_depress.htm‎. 13.Chwastiak L, Ehde DM, Gibbons LE, Sullivan M, Bowen JD, Kraft GH. Depressive symptoms and severity of illness in multiple sclerosis: epidemiologic study of a large community sample. American Journal of Psychiatry. 2002;159 (11):1862-8. 14.Patten SB, Metz LM. Interferon beta1a and depression in secondary progressive MS: data from the SPECTRIMS Trial. Neurology. 2002;59 (5):744-6. 15.Siegert R, Abernethy D. Depression in multiple sclerosis: a review. Journal of Neurology, Neurosurgery & Psychiatry. 2005;76 (4):469-75. 16.Gay MC, Vrignaud P, Garitte C, Meunier C. Predictors of depression in multiple sclerosis patients. Acta neurologica Scandinavica. 2010;121 (3):161-70. 17.Mattioli F, Bellomi F, Stampatori C, Parrinello G, Capra R. Depression, disability and cognitive impairment in multiple sclerosis: a cross sectional Italian study. Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology. 2011;32 (5):825-32. 18.Seyed Saadat SM, Hosseininezhad M, Bakhshayesh B, Seyed Saadat SN, Nabizadeh SP. Prevalence and predictors of depression in Iranian patients with multiple sclerosis: a population-based study. Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology. 2013. 19.McGuigan C, Hutchinson M. Unrecognised symptoms of depression in a community-based population with multiple sclerosis. Journal of neurology. 2006; 253 (2):219-23. 20.Neil Lava. Multiple Sclerosis and Depression 2013. Available from: http://www.webmd.com/multiple-sclerosis/guide/ms-depression?bookmark=true&login=true&pin=false. 21.Nykiel P. Examination of the Psychometric Properties of the Beck Depression Inventory-II: Using the Rasch Measurement Model: ProQuest; 2007. 22.Bamer AM, Cetin K, Johnson KL, Gibbons LE, Ehde DM. Validation study of prevalence and correlates of depressive symptomatology in multiple sclerosis. General hospital psychiatry. 2008;30 (4):311-7. 23.Korostil M, Feinstein A. Anxiety disorders and their clinical correlates in multiple sclerosis patients. Multiple sclerosis (Houndmills, Basingstoke, England). 2007;13 (1):67-72. 24.Beiske AG, Svensson E, Sandanger I, Czujko B, Pedersen ED, Aarseth JH, et al. Depression and anxiety amongst multiple sclerosis patients. European journal of neurology : the official journal of the European Federation of Neurological Societies. 2008;15 (3):239-45. 25.Sajjadi H, Mohaqeqi Kamal SH, Rafiey H, Vameghi M, Forouzan AS, Rezaei M. A systematic review of the prevalence and risk factors of depression among iranian adolescents. Global journal of health science. 2013;5 (3):16-27. 26.Joffe RT. Kaplan and Sadock's Comprehensive Textbook of Psychiatry. 9 ed: Kaplan and Sadock's Comprehensive Textbook of Psychiatry; 2009 June 8, 2009. 27.Labuz-Roszak B, Kubicka-Baczyk K, Pierzchala K, Machowska-Majchrzak A, Skrzypek M. Fatigue and its association with sleep disorders, depressive symptoms and anxiety in patients with multiple sclerosis. Neurologia i neurochirurgia polska. 2012;46 (4):309-17. 28.Williams RM, Turner AP, Hatzakis M, Jr., Bowen JD, Rodriquez AA, Haselkorn JK. Prevalence and correlates of depression among veterans with multiple sclerosis. Neurology. 2005;64 (1):75-80. 29.Feinstein A. Multiple sclerosis and depression. Multiple Sclerosis Journal. 2011;17 (11):1276-81.

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Hosseini F, Ayatollahi P, Behniafard N, Nadi M, Shamsi F, Ferdousian A H. The Prevalence of Depression in Multiple Sclerosis Patients Who Referred to the Multiple Sclerosis Society of Yazd, Iran. Int J Med Invest 2015; 4 (3) :338-343
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