Down syndrome Associated with Epstein’s Anomaly and Pulmonary Hypertension in a 2.5 Months Infant: a Case Report Study

Tanasan, Asadollah; Rostampour, Farshad; jamei Khosroshahy, Ahmad; Sanginabadi, Milad; Falahi, Amin

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Volume 4, Issue 1 (march 2015)

Int J Med Invest 2015, 4(1): 187-190

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Down syndrome Associated with Epstein’s Anomaly and Pulmonary Hypertension in a 2.5 Months Infant: a Case Report Study

Asadollah Tanasan

, Farshad Rostampour ^*

, Ahmad Jamei Khosroshahy

, Milad Sanginabadi

, Amin Falahi

2. General Practitioner, Sirvan Health Network, Ilam University of Medical Sciences and Health Services, Ilam, Iran

Abstract: (11368 Views)

Abstract In children with Down syndrome (DS) there is higher chance for concomitant congenital heart defects and organic disorders. However Epstein’s anomaly is a rare association of DS. We report a 2.5 months DS boy that referred to our hospital with tachypnea. In echocardiography the septal leaflet displaced downwardly toward the apex about 8.2 mm and displacement index was 27.3 mm/m2, Tricuspid regurgitation (TR) was moderate (VC=5.5mm) with 70 mmHg gradient also an ASD with bidirectional shunt and a membranous VSD were seen. catheterisation and angiography was done, pulmonary arterial pressure was subsystemic and a 2.5 mm size PDA was seen, in the levophase a medium size VSD was seen. The patient is under follow up with lanoxin, captopril and lasix now. As mentioned earlier Epstein’s anomaly is rare and it prevalence is about 0.5% of CHDs although 50% of patients with DS have CHD but its association with Epstein’s anomaly is very rare.

Keywords: Down syndrome, Epstein anomaly, Pulmonary Hypertension, Congenital Heart Defect, Tricuspid regurgitation

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Type of Study: Research | Subject: General

References

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Tanasan A, Rostampour F, jamei Khosroshahy A, Sanginabadi M, Falahi A. Down syndrome Associated with Epstein’s Anomaly and Pulmonary Hypertension in a 2.5 Months Infant: a Case Report Study. Int J Med Invest 2015; 4 (1) :187-190
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